diff --git a/src/csharp/Grpc.Core.Tests/AppDomainUnloadTest.cs b/src/csharp/Grpc.Core.Tests/AppDomainUnloadTest.cs
new file mode 100644
index 0000000000000000000000000000000000000000..60aae0e1e573f32fcc3ffafe6ee0575b4bd16553
--- /dev/null
+++ b/src/csharp/Grpc.Core.Tests/AppDomainUnloadTest.cs
@@ -0,0 +1,97 @@
+#region Copyright notice and license
+
+// Copyright 2015, Google Inc.
+// All rights reserved.
+//
+// Redistribution and use in source and binary forms, with or without
+// modification, are permitted provided that the following conditions are
+// met:
+//
+//     * Redistributions of source code must retain the above copyright
+// notice, this list of conditions and the following disclaimer.
+//     * Redistributions in binary form must reproduce the above
+// copyright notice, this list of conditions and the following disclaimer
+// in the documentation and/or other materials provided with the
+// distribution.
+//     * Neither the name of Google Inc. nor the names of its
+// contributors may be used to endorse or promote products derived from
+// this software without specific prior written permission.
+//
+// THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS
+// "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT
+// LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR
+// A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT
+// OWNER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL,
+// SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT
+// LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE,
+// DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY
+// THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+// (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+// OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+
+#endregion
+
+using System;
+using System.Diagnostics;
+using System.Linq;
+using System.Reflection;
+using System.Threading;
+using System.Threading.Tasks;
+using Grpc.Core;
+using Grpc.Core.Internal;
+using Grpc.Core.Utils;
+using NUnit.Framework;
+
+namespace Grpc.Core.Tests
+{
+    public class AppDomainUnloadTest
+    {
+        [Test]
+        public void AppDomainUnloadHookCanCleanupAbandonedCall()
+        {
+            var setup = new AppDomainSetup
+            {
+                ApplicationBase = AppDomain.CurrentDomain.BaseDirectory
+            };
+            var childDomain = AppDomain.CreateDomain("test", null, setup);
+            var remoteObj = childDomain.CreateInstance(typeof(AppDomainTestClass).Assembly.GetName().Name, typeof(AppDomainTestClass).FullName);
+
+            // Try to unload the appdomain once we've created a server and a channel inside the appdomain.
+            AppDomain.Unload(childDomain);
+        }
+
+        public class AppDomainTestClass
+        {
+            const string Host = "127.0.0.1";
+
+            /// <summary>
+            /// Creates a server and a channel and initiates a call. The code is invoked from inside of an AppDomain
+            /// to test if AppDomain.Unload() work if Grpc is being used.
+            /// </summary>
+            public AppDomainTestClass()
+            {
+                AppDomain.CurrentDomain.DomainUnload += (object sender, EventArgs e) =>
+                {
+                    var shutdownChannelsTask = GrpcEnvironment.ShutdownChannelsAsync();
+                    var killServersTask = GrpcEnvironment.KillServersAsync();
+                    Task.WaitAll(shutdownChannelsTask, killServersTask);
+                };
+
+                var helper = new MockServiceHelper(Host);
+                var server = helper.GetServer();
+                server.Start();
+                var channel = helper.GetChannel();
+
+                var readyToShutdown = new TaskCompletionSource<object>();
+                helper.DuplexStreamingHandler = new DuplexStreamingServerMethod<string, string>(async (requestStream, responseStream, context) =>
+                {
+                    readyToShutdown.SetResult(null);
+                    await requestStream.ToListAsync();
+                });
+
+                var call = Calls.AsyncDuplexStreamingCall(helper.CreateDuplexStreamingCall());
+                readyToShutdown.Task.Wait();  // make sure handler is running
+            }
+        }
+    }
+}
diff --git a/src/csharp/Grpc.Core.Tests/Grpc.Core.Tests.csproj b/src/csharp/Grpc.Core.Tests/Grpc.Core.Tests.csproj
index d6adb5bb81c99d4a326ff9181a48fbe9652d0db8..074c9603dcf6e4fd62d95bdb4cebab24ed5e7a97 100644
--- a/src/csharp/Grpc.Core.Tests/Grpc.Core.Tests.csproj
+++ b/src/csharp/Grpc.Core.Tests/Grpc.Core.Tests.csproj
@@ -89,6 +89,7 @@
     <Compile Include="ShutdownHookServerTest.cs" />
     <Compile Include="ShutdownHookPendingCallTest.cs" />
     <Compile Include="ShutdownHookClientTest.cs" />
+    <Compile Include="AppDomainUnloadTest.cs" />
   </ItemGroup>
   <Import Project="$(MSBuildBinPath)\Microsoft.CSharp.targets" />
   <ItemGroup>
diff --git a/src/csharp/tests.json b/src/csharp/tests.json
index 7a106aa0f92b25a5dd6d660520e9a5389cc71163..7e7aee1093a3ddad7b6b5a4ab9562dab234d0275 100644
--- a/src/csharp/tests.json
+++ b/src/csharp/tests.json
@@ -7,6 +7,7 @@
     "Grpc.Core.Internal.Tests.CompletionQueueSafeHandleTest",
     "Grpc.Core.Internal.Tests.MetadataArraySafeHandleTest",
     "Grpc.Core.Internal.Tests.TimespecTest",
+    "Grpc.Core.Tests.AppDomainUnloadTest",
     "Grpc.Core.Tests.CallCredentialsTest",
     "Grpc.Core.Tests.CallOptionsTest",
     "Grpc.Core.Tests.ChannelCredentialsTest",