diff --git a/templates/tools/dockerfile/node_deps.include b/templates/tools/dockerfile/node_deps.include
index 7d37d671467cfc78df9b0e9a960f3445b873c923..7855fbfee366c5871c7b9ce63ac430e4fb606201 100644
--- a/templates/tools/dockerfile/node_deps.include
+++ b/templates/tools/dockerfile/node_deps.include
@@ -4,4 +4,8 @@
 # Install nvm
 RUN touch .profile
 RUN curl -o- https://raw.githubusercontent.com/creationix/nvm/v0.25.4/install.sh | bash
+# Install all versions of node that we want to test
 RUN /bin/bash -l -c "nvm install 0.12 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm install 4 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm install 5 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm alias default 4"
\ No newline at end of file
diff --git a/tools/dockerfile/interoptest/grpc_interop_node/Dockerfile b/tools/dockerfile/interoptest/grpc_interop_node/Dockerfile
index 64314f88642bd1f30834da87e68283f63c0e7e51..2a8d35a5dc144691935bed3c7ef212a4f99fc6fa 100644
--- a/tools/dockerfile/interoptest/grpc_interop_node/Dockerfile
+++ b/tools/dockerfile/interoptest/grpc_interop_node/Dockerfile
@@ -69,8 +69,11 @@ RUN apt-get update && apt-get install -y time && apt-get clean
 # Install nvm
 RUN touch .profile
 RUN curl -o- https://raw.githubusercontent.com/creationix/nvm/v0.25.4/install.sh | bash
+# Install all versions of node that we want to test
 RUN /bin/bash -l -c "nvm install 0.12 && npm config set cache /tmp/npm-cache"
-
+RUN /bin/bash -l -c "nvm install 4 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm install 5 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm alias default 4"
 # Prepare ccache
 RUN ln -s /usr/bin/ccache /usr/local/bin/gcc
 RUN ln -s /usr/bin/ccache /usr/local/bin/g++
diff --git a/tools/dockerfile/interoptest/grpc_interop_node/build_interop.sh b/tools/dockerfile/interoptest/grpc_interop_node/build_interop.sh
index b99fd444eeadfce07819a60d1cd752fc3054953f..976f55d9ab5f514ff1e97b6c3cd49d3cf645fcdd 100755
--- a/tools/dockerfile/interoptest/grpc_interop_node/build_interop.sh
+++ b/tools/dockerfile/interoptest/grpc_interop_node/build_interop.sh
@@ -38,8 +38,6 @@ git clone --recursive /var/local/jenkins/grpc /var/local/git/grpc
 cp -r /var/local/jenkins/service_account $HOME || true
 
 cd /var/local/git/grpc
-nvm use 0.12
-nvm alias default 0.12  # prevent the need to run 'nvm use' in every shell
 
 # build Node interop client & server
 npm install -g node-gyp
diff --git a/tools/dockerfile/stress_test/grpc_interop_stress_node/Dockerfile b/tools/dockerfile/stress_test/grpc_interop_stress_node/Dockerfile
index f70add4e31a8e4f47c45a436548523ab14a4a91f..4fd7cc29a3c7f422c7a4539c18b917d6bf9e5ce3 100644
--- a/tools/dockerfile/stress_test/grpc_interop_stress_node/Dockerfile
+++ b/tools/dockerfile/stress_test/grpc_interop_stress_node/Dockerfile
@@ -69,8 +69,11 @@ RUN apt-get update && apt-get install -y time && apt-get clean
 # Install nvm
 RUN touch .profile
 RUN curl -o- https://raw.githubusercontent.com/creationix/nvm/v0.25.4/install.sh | bash
+# Install all versions of node that we want to test
 RUN /bin/bash -l -c "nvm install 0.12 && npm config set cache /tmp/npm-cache"
-
+RUN /bin/bash -l -c "nvm install 4 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm install 5 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm alias default 4"
 # Google Cloud platform API libraries
 RUN apt-get update && apt-get install -y python-pip && apt-get clean
 RUN pip install --upgrade google-api-python-client
diff --git a/tools/dockerfile/stress_test/grpc_interop_stress_node/build_interop_stress.sh b/tools/dockerfile/stress_test/grpc_interop_stress_node/build_interop_stress.sh
index b99fd444eeadfce07819a60d1cd752fc3054953f..976f55d9ab5f514ff1e97b6c3cd49d3cf645fcdd 100755
--- a/tools/dockerfile/stress_test/grpc_interop_stress_node/build_interop_stress.sh
+++ b/tools/dockerfile/stress_test/grpc_interop_stress_node/build_interop_stress.sh
@@ -38,8 +38,6 @@ git clone --recursive /var/local/jenkins/grpc /var/local/git/grpc
 cp -r /var/local/jenkins/service_account $HOME || true
 
 cd /var/local/git/grpc
-nvm use 0.12
-nvm alias default 0.12  # prevent the need to run 'nvm use' in every shell
 
 # build Node interop client & server
 npm install -g node-gyp
diff --git a/tools/dockerfile/test/multilang_jessie_x64/Dockerfile b/tools/dockerfile/test/multilang_jessie_x64/Dockerfile
index 71ebf2bf715c9eedf251d7d9100123c73407c620..5c3f77405ea15d82159d2da9f57711f2f5c7f7ef 100644
--- a/tools/dockerfile/test/multilang_jessie_x64/Dockerfile
+++ b/tools/dockerfile/test/multilang_jessie_x64/Dockerfile
@@ -90,8 +90,11 @@ RUN apt-get update && apt-get -y install libgflags-dev libgtest-dev libc++-dev c
 # Install nvm
 RUN touch .profile
 RUN curl -o- https://raw.githubusercontent.com/creationix/nvm/v0.25.4/install.sh | bash
+# Install all versions of node that we want to test
 RUN /bin/bash -l -c "nvm install 0.12 && npm config set cache /tmp/npm-cache"
-
+RUN /bin/bash -l -c "nvm install 4 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm install 5 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm alias default 4"
 #=================
 # PHP dependencies
 
diff --git a/tools/dockerfile/test/node_jessie_x64/Dockerfile b/tools/dockerfile/test/node_jessie_x64/Dockerfile
index 64314f88642bd1f30834da87e68283f63c0e7e51..2a8d35a5dc144691935bed3c7ef212a4f99fc6fa 100644
--- a/tools/dockerfile/test/node_jessie_x64/Dockerfile
+++ b/tools/dockerfile/test/node_jessie_x64/Dockerfile
@@ -69,8 +69,11 @@ RUN apt-get update && apt-get install -y time && apt-get clean
 # Install nvm
 RUN touch .profile
 RUN curl -o- https://raw.githubusercontent.com/creationix/nvm/v0.25.4/install.sh | bash
+# Install all versions of node that we want to test
 RUN /bin/bash -l -c "nvm install 0.12 && npm config set cache /tmp/npm-cache"
-
+RUN /bin/bash -l -c "nvm install 4 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm install 5 && npm config set cache /tmp/npm-cache"
+RUN /bin/bash -l -c "nvm alias default 4"
 # Prepare ccache
 RUN ln -s /usr/bin/ccache /usr/local/bin/gcc
 RUN ln -s /usr/bin/ccache /usr/local/bin/g++
diff --git a/tools/gce/linux_performance_worker_init.sh b/tools/gce/linux_performance_worker_init.sh
index 25ac3bcedea29789148f7497e5f098546315bb84..df29581e69a3abea9f13d9b4e4931c56c53692b3 100755
--- a/tools/gce/linux_performance_worker_init.sh
+++ b/tools/gce/linux_performance_worker_init.sh
@@ -95,6 +95,9 @@ sudo pip install tox
 touch .profile
 curl -o- https://raw.githubusercontent.com/creationix/nvm/v0.25.4/install.sh | bash
 nvm install 0.12 && npm config set cache /tmp/npm-cache
+nvm install 4 && npm config set cache /tmp/npm-cache
+nvm install 5 && npm config set cache /tmp/npm-cache
+nvm alias default 4
 
 # C# dependencies (http://www.mono-project.com/docs/getting-started/install/linux/#debian-ubuntu-and-derivatives)
 
diff --git a/tools/run_tests/performance/run_worker_node.sh b/tools/run_tests/performance/run_worker_node.sh
index 46b6ff0177412c4559f8c31cd22386937dc6cbde..9a53a311f40b60f9aac90b48363c5bb4048dedeb 100755
--- a/tools/run_tests/performance/run_worker_node.sh
+++ b/tools/run_tests/performance/run_worker_node.sh
@@ -29,7 +29,7 @@
 # OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
 
 source ~/.nvm/nvm.sh
-nvm use 0.12
+nvm use 4
 
 set -ex
 
diff --git a/tools/run_tests/run_tests.py b/tools/run_tests/run_tests.py
index dea481ef90ddcbafce4f2ae476201c669f03dd8b..d50d5aac95e927d286655099dc3f13a5989e4af6 100755
--- a/tools/run_tests/run_tests.py
+++ b/tools/run_tests/run_tests.py
@@ -272,12 +272,17 @@ class NodeLanguage(object):
 
   def __init__(self):
     self.platform = platform_string()
-    self.node_version = '0.12'
 
   def configure(self, config, args):
     self.config = config
     self.args = args
-    _check_compiler(self.args.compiler, ['default'])
+    _check_compiler(self.args.compiler, ['default', 'node0.12',
+                                         'node4', 'node5'])
+    if self.args.compiler == 'default':
+      self.node_version = '4'
+    else:
+      # Take off the word "node"
+      self.node_version = self.args.compiler[4:]
 
   def test_specs(self):
     if self.platform == 'windows':
@@ -802,7 +807,8 @@ argp.add_argument('--compiler',
                            'gcc4.4', 'gcc4.9', 'gcc5.3',
                            'clang3.4', 'clang3.6',
                            'vs2010', 'vs2013', 'vs2015',
-                           'python2.7', 'python3.4'],
+                           'python2.7', 'python3.4',
+                           'node0.12', 'node4', 'node5'],
                   default='default',
                   help='Selects compiler to use. Allowed values depend on the platform and language.')
 argp.add_argument('--build_only',