diff --git a/src/csharp/Grpc.IntegrationTesting/InteropClientServerTest.cs b/src/csharp/Grpc.IntegrationTesting/InteropClientServerTest.cs
index f6cdfa1d12a536204e6ab551ca77ebd5a3e4f988..18168f99704f4a076a3eddf2f8ba8e93f439214b 100644
--- a/src/csharp/Grpc.IntegrationTesting/InteropClientServerTest.cs
+++ b/src/csharp/Grpc.IntegrationTesting/InteropClientServerTest.cs
@@ -147,6 +147,7 @@ namespace Grpc.IntegrationTesting
         }
 
         [Test]
+        [Ignore("TODO: see #4427")]
         public void UnimplementedMethod()
         {
             InteropClient.RunUnimplementedMethod(UnimplementedService.NewClient(channel));