diff --git a/tools/run_tests/artifacts/artifact_targets.py b/tools/run_tests/artifacts/artifact_targets.py
index e0658f4678d37018ab72bbd67c5b90191e41de4d..04702baccaeba3afe99b21d18c2146e8acf24388 100644
--- a/tools/run_tests/artifacts/artifact_targets.py
+++ b/tools/run_tests/artifacts/artifact_targets.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2016, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/artifacts/distribtest_targets.py b/tools/run_tests/artifacts/distribtest_targets.py
index a7535b385216bb0f4c98540826dedd38e2ebd4e0..90bbde83cf4f3ca80a39a56b86b3c35ef7e120f8 100644
--- a/tools/run_tests/artifacts/distribtest_targets.py
+++ b/tools/run_tests/artifacts/distribtest_targets.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2016, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/artifacts/package_targets.py b/tools/run_tests/artifacts/package_targets.py
index d490f571c37f684574dbbb30b13d903b160c0116..2547f2073cfa244f4e177c0534044e070e711510 100644
--- a/tools/run_tests/artifacts/package_targets.py
+++ b/tools/run_tests/artifacts/package_targets.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2016, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/performance/bq_upload_result.py b/tools/run_tests/performance/bq_upload_result.py
index e2e1393509eab1b5b0c067257d8a43b09b7eaeab..3bac1199a7bee21815410a89a650c162299d7a49 100755
--- a/tools/run_tests/performance/bq_upload_result.py
+++ b/tools/run_tests/performance/bq_upload_result.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2016, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/python_utils/antagonist.py b/tools/run_tests/python_utils/antagonist.py
index 857addfb38658a80f344a75d7526f8c5a1cc5ba0..111839ccf932073e78b7e9af99acd3d08521cf96 100755
--- a/tools/run_tests/python_utils/antagonist.py
+++ b/tools/run_tests/python_utils/antagonist.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2015, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/python_utils/filter_pull_request_tests.py b/tools/run_tests/python_utils/filter_pull_request_tests.py
index 041e3491627973107ee5f660b8c21ab7b03606dc..e013376295980f5520dc3d80126387b065e3765a 100644
--- a/tools/run_tests/python_utils/filter_pull_request_tests.py
+++ b/tools/run_tests/python_utils/filter_pull_request_tests.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2015, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/python_utils/port_server.py b/tools/run_tests/python_utils/port_server.py
index e9b3f7ff7957c4fdfbea8d1be2dbbbc96ba55176..dbd32efc0e8eab22abb94cb667177195f20e6c45 100755
--- a/tools/run_tests/python_utils/port_server.py
+++ b/tools/run_tests/python_utils/port_server.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2015, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/run_build_statistics.py b/tools/run_tests/run_build_statistics.py
index e33e01e70349a424eb347a48507f5bdbad298c22..dd11a45e789b3d97a25c9b988e19bfdb4136bb25 100755
--- a/tools/run_tests/run_build_statistics.py
+++ b/tools/run_tests/run_build_statistics.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2016, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/run_interop_tests.py b/tools/run_tests/run_interop_tests.py
index ace142ed8ad872b0d0349626feab93c6db109b32..29d5a9aaa008fa41ef46eb17ee2d41be8ee099da 100755
--- a/tools/run_tests/run_interop_tests.py
+++ b/tools/run_tests/run_interop_tests.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2015, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/run_microbenchmark.py b/tools/run_tests/run_microbenchmark.py
index 94711109680d6ffe68c3c212a6aadd0f7183bb11..57b2636e56955aa2dbc50eaf3871c55b5d300277 100755
--- a/tools/run_tests/run_microbenchmark.py
+++ b/tools/run_tests/run_microbenchmark.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2017, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/run_performance_tests.py b/tools/run_tests/run_performance_tests.py
index c79f47a31753fc0cfa17bd9f8a595b8bce44272c..35d20be5b75d2abf58b37ed55316cf930fcbfd90 100755
--- a/tools/run_tests/run_performance_tests.py
+++ b/tools/run_tests/run_performance_tests.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2016, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/run_stress_tests.py b/tools/run_tests/run_stress_tests.py
index 3a2661a9aa66200a05fd39762af03b11773cc3fd..4eea02118e54682f5c6e26b36f53c7fdaa11966f 100755
--- a/tools/run_tests/run_stress_tests.py
+++ b/tools/run_tests/run_stress_tests.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2015, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/run_tests_matrix.py b/tools/run_tests/run_tests_matrix.py
index 191228e4db78771174696f3edc0f76b9c14fb4ba..b9a9bd52f64d69d91d2a073a08280703e5884691 100755
--- a/tools/run_tests/run_tests_matrix.py
+++ b/tools/run_tests/run_tests_matrix.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2015, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/sanity/check_sources_and_headers.py b/tools/run_tests/sanity/check_sources_and_headers.py
index 0bb92fda8b54cc75859014547118bf4cb12f7758..f2e0bfeb3d45dafa7abaffd4571063e999d1bff9 100755
--- a/tools/run_tests/sanity/check_sources_and_headers.py
+++ b/tools/run_tests/sanity/check_sources_and_headers.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2015, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/sanity/check_test_filtering.py b/tools/run_tests/sanity/check_test_filtering.py
index aceee6d4d72fa3ba05f8fa39c9b7f8a4573d2ddb..ba03f1120923e447d7509478a2850849fe5afc2d 100755
--- a/tools/run_tests/sanity/check_test_filtering.py
+++ b/tools/run_tests/sanity/check_test_filtering.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 
 # Copyright 2016, Google Inc.
 # All rights reserved.
diff --git a/tools/run_tests/sanity/check_version.py b/tools/run_tests/sanity/check_version.py
index d8162fb3c57cc57aced0159bdfdb994e4ee3abfd..d247260dbbbb1351dff5e1916f9e9fdeb3ae98d4 100755
--- a/tools/run_tests/sanity/check_version.py
+++ b/tools/run_tests/sanity/check_version.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 
 # Copyright 2016, Google Inc.
 # All rights reserved.
diff --git a/tools/run_tests/sanity/core_banned_functions.py b/tools/run_tests/sanity/core_banned_functions.py
index c1069ccfb8439664c61d9cd72678877b1449b4ef..c3c3cbec767b96403b2479f38412bfee12df2300 100755
--- a/tools/run_tests/sanity/core_banned_functions.py
+++ b/tools/run_tests/sanity/core_banned_functions.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 
 # Copyright 2016, Google Inc.
 # All rights reserved.
diff --git a/tools/run_tests/stress_test/print_summary.py b/tools/run_tests/stress_test/print_summary.py
index cb1a33961e45a5cb05895c3c232ddefaba2faa56..6f4ada2f4fd23a6e341323f25f2f2b198ae71dee 100755
--- a/tools/run_tests/stress_test/print_summary.py
+++ b/tools/run_tests/stress_test/print_summary.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2016, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/stress_test/run_on_gke.py b/tools/run_tests/stress_test/run_on_gke.py
index a2a5f42a2c674d8467e0b0f7ab955f792becf2c2..b190ebde7a4f44d697b7eab4b23515755a6553d6 100755
--- a/tools/run_tests/stress_test/run_on_gke.py
+++ b/tools/run_tests/stress_test/run_on_gke.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2015-2016, Google Inc.
 # All rights reserved.
 #
diff --git a/tools/run_tests/task_runner.py b/tools/run_tests/task_runner.py
index fdc46682223fed735454c3bb585bc8e0550b2f5d..0ec7efbbee6493da9e3b4778b8fee3e27730d13b 100755
--- a/tools/run_tests/task_runner.py
+++ b/tools/run_tests/task_runner.py
@@ -1,4 +1,4 @@
-#!/usr/bin/env python2.7
+#!/usr/bin/env python
 # Copyright 2016, Google Inc.
 # All rights reserved.
 #